The average bus between Santander and Osuna takes 23h 58m and the fastest bus takes 20h 50m. The bus service runs several times per day from Santander to Osuna. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run twice daily between Santander and Osuna. The earliest departure is at 6:45 AM in the morning, and the last departure from Santander is at 7:30 PM which arrives into Osuna at 4:20 PM. All services require a transfer at Bilbao Intermodal and take an average of 23h 58m. The schedules shown below are for the next available departures.
Arrives next day


26h 35m • 2 changes
Arrives next day


21h 5m • 2 changes
Arrives next day


26h 35m • 2 changes
Arrives next day


21h 5m • 2 changes
Arrives next day


26h 35m • 2 changes
Arrives next day


21h 5m • 2 changes
Want to know about travelling from Santander to Osuna? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from Santander to Osuna. However, there are services departing from Santander station and arriving at Osuna station via Bilbao Intermodal. The journey, including transfers, takes approximately 23h 58m.
Santander to Osuna bus services, operated by ALSA, depart from Estación de autobuses de Santander station.
Santander to Osuna bus services, operated by ALSA, arrive at Osuna station.
The distance between Santander and Osuna is 701.1 km. The road distance is 1,145 km.
You can take a bus from Estación de autobuses de Santander to Osuna via Bilbao Intermodal and Sevilla, Estación de Autobuses (Plaza de Armas) in around 17h 30m.