The average bus between Santander and Medina de Ríoseco takes 5h 31m and the fastest bus takes 4h 30m. The bus service runs several times per day from Santander to Medina de Ríoseco. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run 3 times a day between Santander and Medina de Ríoseco. The earliest departure is at 9:00 AM in the morning, and the last departure from Santander is at 9:00 PM which arrives into Medina de Ríoseco at 1:30 AM. All services require a transfer, and take on average 5h 31m. The schedules shown below are for the next available departures.

4h 45m • 1 change

4h 55m • 1 change
Arrives next day

7h 30m • 1 change

4h 45m • 1 change

4h 55m • 1 change
Arrives next day

7h 30m • 1 change

4h 45m • 1 change

4h 55m • 1 change
Arrives next day

7h 30m • 1 change

4h 45m • 1 change

4h 55m • 1 change
Arrives next day

7h 30m • 1 change
Want to know about travelling from Santander to Medina de Ríoseco? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from Santander to Medina de Ríoseco. However, there are services departing from Santander station and arriving at Medina de Ríoseco station via Valladolid. The journey, including transfers, takes approximately 5h 31m.
Santander to Medina de Ríoseco bus services, operated by ALSA, depart from Santander E.A. station.
Santander to Medina de Ríoseco bus services, operated by ALSA, arrive at Medina Rioseco station.
Book your Santander to Medina de Ríoseco bus tickets online with ALSA.
The distance between Santander and Medina de Ríoseco is 202.9 km. The road distance is 294 km.
You can take a bus from Santander E.A. to Medina Rioseco via Valladolid in around 4h 45m.