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Santander to Italy buses

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Trip Overview

The average bus between Santander and Italy takes 47h 9m and the fastest bus takes 47h 4m. The bus runs, on average, 4 times per week from Santander to Italy. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.

47h 9m
Duration
1,992 km
Distance
€208
Average price
4 times a week
Frequency

Santander to Italy bus times

Buses run 4 times a week between Santander and Italy. The service departs Santander at 5:50 PM in the evening, which arrives into Italy at 17:54:32. All services require a transfer at Bordeaux and take an average of 47h 9m. The schedules shown below are for the next available departures.

Departing Thursday, November 5, 2026

  •  → 

    Arrives +2 days

    FlixBusFlixBusFlixBusATAC S.p.A. Azienda per la mobilità47h 4m • 3 changes

Departing Friday, November 6, 2026

  •  → 

    Arrives +2 days

    FlixBusFlixBusFlixBusATAC S.p.A. Azienda per la mobilità47h 7m • 3 changes

Departing Saturday, November 7, 2026

  •  → 

    Arrives +2 days

    FlixBusFlixBusFlixBusATAC S.p.A. Azienda per la mobilità47h 12m • 3 changes

Departing Sunday, November 8, 2026

  •  → 

    Arrives +2 days

    FlixBusFlixBusFlixBusATAC S.p.A. Azienda per la mobilità47h 12m • 3 changes

Frequently asked questions

Want to know about travelling from Santander to Italy? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.

Map of how to get from Santander to Italy.ExpandLaunch map view
  • Distance: 1,991.5 km
  • Duration: 47h 9m

What companies run services between Santander, Spain and Italy?

You can take a bus from Estación de autobuses de Santander to Termini via Bordeaux, Florence Villa Constanza Bus Station, and Roma, Autostazione Tiburtina in around 28h 12m.

Operators