The average bus between Santander and Huelva takes 22h 58m and the fastest bus takes 18h. The bus service runs several times per day from Santander to Huelva. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run twice daily between Santander and Huelva. The earliest departure is at 2:30 AM at night, and the last departure from Santander is at 7:00 PM which arrives into Huelva at 1:00 PM. All services require a transfer at Madrid, Avenida de América and take an average of 22h 58m. The schedules shown below are for the next available departures.
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30h 30m • 2 changesArrives next day


18h • 2 changesWant to know about travelling from Santander to Huelva? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from Santander to Huelva. However, there are services departing from Santander station and arriving at Huelva station via Madrid, Avenida de América. The journey, including transfers, takes approximately 22h 58m.
Santander to Huelva bus services, operated by ALSA, depart from Estación de autobuses de Santander station.
Santander to Huelva bus services, operated by ALSA, arrive at Huelva station.
Book your Santander to Huelva bus tickets online with ALSA, Socibus and Damas.
The distance between Santander and Huelva is 738.5 km. The road distance is 1,035 km.
You can take a bus from Estación de autobuses de Santander to Huelva via Madrid, Avenida de América, Intercambiador Av América Metro, Madrid Méndez Alvaro, and Madrid Estación Sur de Autobuses in around 17h 11m.