Rome2Rio

Santander to Brussels buses

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Trip Overview

The bus between Santander and Brussels takes 19h 45m. There is at least one bus per day from Santander to Brussels. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.

19h 45m
Duration
1,337 km
Distance
€140
Average price
Once daily
Frequency

Santander to Brussels bus times

Buses run once daily between Santander and Brussels. The service departs Santander at 1:00 PM in the afternoon, which arrives into Brussels at 07:45:00. All services require a transfer at Bilbao Intermodal and take an average of 19h 45m. The schedules shown below are for the next available departures.

Departing Friday, November 6, 2026

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    Arrives next day

    ALSAFlixBus19h 45m • 1 change

Departing Saturday, November 7, 2026

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    Arrives next day

    ALSAFlixBus19h 45m • 1 change

Departing Sunday, November 8, 2026

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    Arrives next day

    ALSAFlixBus19h 45m • 1 change

Departing Monday, November 9, 2026

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    Arrives next day

    ALSAFlixBus19h 45m • 1 change

Departing Tuesday, November 10, 2026

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    Arrives next day

    ALSAFlixBus19h 45m • 1 change

Departing Wednesday, November 11, 2026

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    Arrives next day

    ALSAFlixBus19h 45m • 1 change

Departing Thursday, November 12, 2026

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    Arrives next day

    ALSAFlixBus19h 45m • 1 change

Frequently asked questions

Want to know about travelling from Santander to Brussels? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.

Map of how to get from Santander to Brussels.ExpandLaunch map view
  • Distance: 1,336.5 km
  • Duration: 19h 45m

What companies run services between Santander, Spain and Brussels, Belgium?

You can take a bus from Estación de autobuses de Santander to Brussels-North train station via Bilbao Intermodal and Bilbao in around 20h 40m.

Operators