The average bus between Santa Ana and Indio takes 6h 26m and the fastest bus takes 4h 14m. The bus service runs several times per day from Santa Ana to Indio. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run every 4 hours between Santa Ana and Indio. The earliest departure is at 12:05 AM at night, and the last departure from Santa Ana is at 7:45 PM which arrives into Indio at 11:59 PM. All services require a transfer, and take on average 6h 26m. The schedules shown below are for the next available departures.

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Want to know about travelling from Santa Ana to Indio? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from Santa Ana to Indio. However, there are services departing from Santa Ana station and arriving at Indio station via Huntington Park. The journey, including transfers, takes approximately 6h 26m.
Santa Ana to Indio bus services, operated by CBX Cross Border Express, depart from Santa Ana station.
Santa Ana to Indio bus services, operated by CBX Cross Border Express, arrive at Indio station.
Book your Santa Ana to Indio bus tickets online with CBX Cross Border Express, Tufesa and 2 other operators.
The distance between Santa Ana and Indio is 152.7 km. The road distance is 264 km.
You can take a bus from Santa Ana to Indio via Huntington Park in around 4h 11m.