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Santa Ana to Guaymas buses

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Trip Overview

The average bus between Santa Ana and Guaymas takes 21h 35m and the fastest bus takes 18h 20m. There is at least one bus per day from Santa Ana to Guaymas. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.

21h 35m
Duration
1,389 km
Distance
$3,018
Average price
Once daily
Frequency

Santa Ana to Guaymas bus times

Buses run once daily between Santa Ana and Guaymas. The earliest departure is at 1:00 AM at night, and the last departure from Santa Ana is at 10:00 PM which arrives into Guaymas at 2:20 PM. All services require a transfer, and take on average 21h 35m. The schedules shown below are for the next available departures.

Departing Sunday, November 15, 2026

  •  → 

    Arrives next day

    Limousine ExpressTufesa Mexico28h 50m • 1 change
  •  → 

    Arrives next day

    CBX Cross Border ExpressTufesa Mexico20h • 1 change
  •  → 

    Arrives next day

    Limousine ExpressTufesa Mexico18h 20m • 1 change

Departing Monday, November 16, 2026

  •  → 

    Arrives next day

    Limousine ExpressTufesa Mexico28h 50m • 1 change
  •  → 

    Arrives next day

    CBX Cross Border ExpressTufesa Mexico20h • 1 change
  •  → 

    Arrives next day

    Limousine ExpressTufesa Mexico18h 20m • 1 change

Frequently asked questions

Want to know about travelling from Santa Ana to Guaymas? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.

Map of how to get from Santa Ana to Guaymas.ExpandLaunch map view
  • Distance: 1,389.3 km
  • Duration: 21h 35m

What companies run services between Santa Ana, CA, USA and Guaymas, Mexico?

You can take a bus from Santa Ana to Guaymas via Huntington Park in around 18h 50m.

Operators