The average bus between Sambuca and Rome takes 6h 51m and the fastest bus takes 5h 2m. The bus service runs several times per day from Sambuca to Rome. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run every 4 hours between Sambuca and Rome. The earliest departure is at 6:23 AM in the morning, and the last departure from Sambuca is at 8:23 PM which arrives into Rome at 8:40 AM. All services require a transfer at Poggibonsi Fs and take an average of 6h 51m. The schedules shown below are for the next available departures.


5h 2m • 2 changes


6h 8m • 2 changes


6h 54m • 2 changes


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6h 8m • 2 changes


6h 27m • 2 changes


6h 54m • 2 changes


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6h 8m • 2 changes


5h 29m • 2 changes


5h 13m • 2 changes


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7h 14m • 2 changes
Arrives next day


12h 16m • 2 changes


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6h 8m • 2 changes


6h 27m • 2 changes


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6h 54m • 2 changes


5h 9m • 2 changes
Want to know about travelling from Sambuca to Rome? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from Sambuca to Rome. However, there are services departing from Sambuca station and arriving at Rome station via Roma, Autostazione Tiburtina. The journey, including transfers, takes approximately 6h 51m.
Sambuca to Rome bus services, operated by Autolinee Toscane, depart from Siena station.
Sambuca to Rome bus services, operated by Autolinee Toscane, arrive at Roma, Autostazione Tiburtina station.
The distance between Sambuca and Rome is 212.9 km. The road distance is 291 km.
FlixBus operates a bus from Siena to Roma, Autostazione Tiburtina every 3 hours. Tickets cost €16–27 and the journey takes 2h 50m. AutoLinee Moretti also services this route 3 times a week.