The average bus between Sambuca and Rome takes 6h 52m and the fastest bus takes 5h 2m. The bus service runs several times per day from Sambuca to Rome. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run every 4 hours between Sambuca and Rome. The earliest departure is at 6:23 AM in the morning, and the last departure from Sambuca is at 8:23 PM which arrives into Rome at 8:40 AM. All services require a transfer at Poggibonsi Fs and take an average of 6h 52m. The schedules shown below are for the next available departures.


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5h 9m • 2 changes

5h 2m • 2 changes

6h 18m • 2 changes

7h 52m • 2 changes

6h 54m • 2 changes

5h 2m • 2 changes

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6h 27m • 2 changes

6h 54m • 2 changesWant to know about travelling from Sambuca to Rome? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from Sambuca to Rome. However, there are services departing from Siena station and arriving at Roma, Autostazione Tiburtina station via Roma, Autostazione Tiburtina station. The journey, including transfers, takes approximately 6h 52m.
Sambuca to Rome bus services, operated by FlixBus, depart from Siena station.
Sambuca to Rome bus services, operated by FlixBus, arrive at Roma, Autostazione Tiburtina station.
The distance between Sambuca and Rome is 212.9 km. The road distance is 263 km.
FlixBus operates a bus from Siena to Roma, Autostazione Tiburtina hourly. Tickets cost €20–30 and the journey takes 2h 50m. AutoLinee Moretti also services this route 3 times a week.