The average bus between Ruislip and Southampton takes 3h and the fastest bus takes 2h 35m. There is a bus service every few hours from Ruislip to Southampton. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run hourly between Ruislip and Southampton. The earliest departure is at 6:10 AM in the morning, and the last departure from Ruislip is at 11:55 PM which arrives into Southampton at 3:00 AM. All services require a transfer, and take on average 3h. The schedules shown below are for the next available departures.

2h 55m • 1 change

2h 55m • 1 change

3h 10m • 1 change

3h 10m • 1 change

2h 55m • 1 change

2h 45m • 1 change

2h 55m • 1 change

2h 55m • 1 change

2h 55m • 1 change

2h 45m • 1 change

2h 55m • 1 change

2h 55m • 1 change

3h 20m • 1 change

3h 9m • 1 change

2h 54m • 1 change

2h 54m • 1 change
Want to know about travelling from Ruislip to Southampton? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from Ruislip to Southampton. However, there are services departing from Ruislip station and arriving at Southampton station via Heathrow Central Bus Station station. The journey, including transfers, takes approximately 3h.
Ruislip to Southampton bus services, operated by Abellio London, depart from Brickwall Lane station.
Ruislip to Southampton bus services, operated by Abellio London, arrive at Coach Station.
The distance between Ruislip and Southampton is 101 km. The road distance is 126 km.
You can take a bus from Brickwall Lane to Coach Station via Heathrow Central Bus Station in around 3h 15m.