The average bus between Ruislip and Southampton takes 3h 1m and the fastest bus takes 2h 30m. There is a bus service every few hours from Ruislip to Southampton. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run hourly between Ruislip and Southampton. The earliest departure is at 6:10 AM in the morning, and the last departure from Ruislip is at 11:55 PM which arrives into Southampton at 3:10 AM. All services require a transfer, and take on average 3h 1m. The schedules shown below are for the next available departures.

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2h 45m • 1 change
2h 55m • 1 change
2h 50m • 1 change
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3h 15m • 1 change
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3h 5m • 1 changeWant to know about travelling from Ruislip to Southampton? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from Ruislip to Southampton. However, there are services departing from Brickwall Lane station and arriving at Coach Station via Heathrow Central Bus Station. The journey, including transfers, takes approximately 3h 1m.
Ruislip to Southampton bus services, operated by Transport UK London Bus, depart from Brickwall Lane station.
Ruislip to Southampton bus services, operated by National Express, arrive at Coach Station.
Book your Ruislip to Southampton bus tickets online with Omio.
The distance between Ruislip and Southampton is 101 km. The road distance is 115 km.
You can take a bus from Brickwall Lane to Coach Station via Heathrow Central Bus Station in around 3h 15m.