The average bus between Rome and Santa Rufina takes 2h 39m and the fastest bus takes 1h 42m. The bus service runs several times per day from Rome to Santa Rufina. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run twice daily between Rome and Santa Rufina. The earliest departure is at 4:56 AM at night, and the last departure from Rome is at 8:09 PM which arrives into Santa Rufina at 10:31 PM. All services require a transfer, and take on average 2h 39m. The schedules shown below are for the next available departures.

1h 55m • 1 change

2h 26m • 1 change

2h 15m • 1 change

2h 36m • 1 change
Want to know about travelling from Rome to Santa Rufina? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from Rome to Santa Rufina. However, there are services departing from Rome station and arriving at Santa Rufina station via RIETI | Piazza Cavour # f1068. The journey, including transfers, takes approximately 2h 39m.
Rome to Santa Rufina bus services, operated by Cotral S.p.A., depart from ROMA | Stazione Nomentana FS station.
Rome to Santa Rufina bus services, operated by Cotral S.p.A., arrive at RIETI | Piazza Cavour # f1068 station.
The distance between Rome and Santa Rufina is 66.5 km. The road distance is 83 km.
Cotral S.p.A. operates a bus from ROMA | Stazione Nomentana FS to RIETI | Piazza Cavour # f1068 hourly. Tickets cost €4–6 and the journey takes 1h 32m.