The average bus between Rome and Lugano takes 11h 35m and the fastest bus takes 9h 45m. The bus service runs several times per day from Rome to Lugano. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run 4 times a day between Rome and Lugano. The earliest departure is at 12:15 AM at night, and the last departure from Rome is at 10:45 PM which arrives into Lugano at 7:20 AM. All services require a transfer, and take on average 11h 35m. The schedules shown below are for the next available departures.

10h 15m • 1 change

10h 20m • 1 change
Arrives next day

8h 35m • 1 change

9h 55m • 1 change

10h 15m • 1 change

7h 45m • 1 change
Arrives next day

8h 35m • 1 change

9h 55m • 1 change

10h 15m • 1 change

10h 20m • 1 change
Arrives next day

8h 35m • 1 change

10h 50m • 1 change

10h 15m • 1 change

7h 45m • 1 change
Arrives next day

8h 35m • 1 change

10h 50m • 1 change

10h 15m • 1 change

10h 20m • 1 change
Arrives next day

8h 35m • 1 change
Want to know about travelling from Rome to Lugano? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from Rome to Lugano. However, there are services departing from Rome station and arriving at Lugano station via Milano, Autostazione Lampugnano. The journey, including transfers, takes approximately 11h 35m.
Rome to Lugano bus services, operated by FlixBus, depart from Roma, Autostazione Tiburtina station.
Rome to Lugano bus services, operated by FlixBus, arrive at Lugano station.
Book your Rome to Lugano bus tickets online with FlixBus.
The distance between Rome and Lugano is 537.5 km. The road distance is 677 km.
You can take a bus from Roma, Autostazione Tiburtina to Lugano via Milan in around 10h 25m.