The average bus between Rome and Lizzanello takes 10h 52m and the fastest bus takes 8h 55m. The bus service runs several times per day from Rome to Lizzanello. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run 3 times a day between Rome and Lizzanello. The earliest departure is at 9:15 AM in the morning, and the last departure from Rome is at 11:45 PM which arrives into Lizzanello at 12:00 PM. All services require a transfer, and take on average 10h 52m. The schedules shown below are for the next available departures.

10h • 1 change

9h 25m • 1 change
Arrives next day

14h 40m • 1 change
Arrives next day

12h 15m • 1 change

10h • 1 change

9h 25m • 1 change
Arrives next day

16h 10m • 1 change
Arrives next day

12h 15m • 1 change

10h • 1 change

9h 25m • 1 change
Arrives next day

8h 55m • 1 change
Arrives next day

12h 15m • 1 change

10h • 1 change

9h 25m • 1 change
Arrives next day

8h 55m • 1 change
Arrives next day

12h 15m • 1 change
Want to know about travelling from Rome to Lizzanello? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from Rome to Lizzanello. However, there are services departing from Rome station and arriving at Lizzanello station via Lecce. The journey, including transfers, takes approximately 10h 52m.
Rome to Lizzanello bus services, operated by FlixBus, depart from Roma, Autostazione Tiburtina station.
Rome to Lizzanello bus services, operated by FlixBus, arrive at Lecce station.
The distance between Rome and Lizzanello is 511.1 km. The road distance is 621 km.
FlixBus operates a bus from Roma, Autostazione Tiburtina to Lecce every 4 hours. Tickets cost €40–75 and the journey takes 8h 20m.