The average bus between Roma Termini and Termoli takes 5h 52m and the fastest bus takes 4h 12m. The bus service runs several times per day from Roma Termini to Termoli. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run twice daily between Roma Termini and Termoli. The earliest departure is at 5:35 AM in the morning, and the last departure from Roma Termini is at 10:38 PM which arrives into Termoli at 3:35 AM. All services require a transfer, and take on average 5h 52m. The schedules shown below are for the next available departures.

5h 2m • 1 change

5h 25m • 1 change
Arrives next day

4h 56m • 1 change

5h 2m • 1 change

5h 25m • 1 change
Arrives next day

4h 56m • 1 change

5h 4m • 1 change

5h 23m • 1 change
Arrives next day

5h 4m • 1 change
Want to know about travelling from Roma Termini to Termoli? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from Roma Termini to Termoli. However, there are services departing from Roma Termini station and arriving at Termoli station via Termoli. The journey, including transfers, takes approximately 5h 52m.
Roma Termini to Termoli bus services, operated by ATAC S.p.A. Azienda per la mobilità, depart from Roma, Autostazione Tiburtina station.
Roma Termini to Termoli bus services, operated by ATAC S.p.A. Azienda per la mobilità, arrive at Termoli station.
The distance between Roma Termini and Termoli is 206.4 km. The road distance is 327 km.
FlixBus operates a bus from Roma, Autostazione Tiburtina to Termoli 3 times a day. Tickets cost €22–40 and the journey takes 4h 25m. ATM Azienda di Trasporti Molisana S.p.A. also services this route once daily.