The average bus between Roma Termini and Perugia takes 2h 57m and the fastest bus takes 2h 34m. The bus service runs several times per day from Roma Termini to Perugia. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run 4 times a day between Roma Termini and Perugia. The earliest departure is at 5:35 AM in the morning, and the last departure from Roma Termini is at 11:55 PM which arrives into Perugia at 2:55 AM. All services require a transfer, and take on average 2h 57m. The schedules shown below are for the next available departures.

2h 58m • 1 change
Arrives next day

2h 34m • 1 change
Arrives next day

3h • 1 change

3h 8m • 1 change

2h 50m • 1 change

3h • 1 change

3h 5m • 1 change
Want to know about travelling from Roma Termini to Perugia? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from Roma Termini to Perugia. However, there are services departing from Roma Termini station and arriving at Perugia station via Perugia. The journey, including transfers, takes approximately 2h 57m.
Roma Termini to Perugia bus services, operated by ATAC S.p.A. Azienda per la mobilità, depart from Roma, Autostazione Tiburtina station.
Roma Termini to Perugia bus services, operated by ATAC S.p.A. Azienda per la mobilità, arrive at Perugia station.
The distance between Roma Termini and Perugia is 135 km. The road distance is 175 km.
FlixBus operates a bus from Roma, Autostazione Tiburtina to Perugia every 4 hours. Tickets cost €12–21 and the journey takes 2h 20m. Three other operators also service this route.