The average bus between Rochester and Harlem takes 7h 33m and the fastest bus takes 6h 45m. The bus service runs several times per day from Rochester to Harlem. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run 4 times a day between Rochester and Harlem. The earliest departure is at 12:55 AM at night, and the last departure from Rochester is at 4:05 PM which arrives into Harlem at 11:12 PM. All services require a transfer, and take on average 7h 33m. The schedules shown below are for the next available departures.

6h 57m • 1 change

7h 30m • 1 change

8h 15m • 1 change

7h 41m • 1 change

6h 57m • 1 change

7h 30m • 1 change

8h 15m • 1 change

7h 41m • 1 change

6h 45m • 1 change

7h 28m • 1 change

8h 14m • 1 change

7h 32m • 1 change

6h 54m • 1 change

7h 25m • 1 change

8h 16m • 1 change

7h 33m • 1 change
Want to know about travelling from Rochester to Harlem? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from Rochester to Harlem. However, there are services departing from Rochester station and arriving at Harlem station via New York. The journey, including transfers, takes approximately 7h 33m.
Rochester to Harlem bus services, operated by Trailways, depart from Rochester station.
Rochester to Harlem bus services, operated by Trailways, arrive at New York station.
The distance between Rochester and Harlem is 400.1 km. The road distance is 624 km.
Trailways operates a bus from Rochester to New York every 4 hours. Tickets cost $50–230 and the journey takes 6h 15m.