Bus Relais Orso, Rome to Florence from €28 | Tickets & Timetables

Trip Overview

The average bus between Relais Orso, Rome and Florence takes 4h 29m and the fastest bus takes 3h 56m. There is a bus service every few hours from Relais Orso, Rome to Florence. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.

4h 29m
Duration: 285 km
Distance: €28
Average price: Hourly
Frequency

Bus

best

Take the bus from Roma, Autostazione Tiburtina to Florence Villa Constanza Bus Stationbus 510 / ...

4h 34m

€14–47

Relais Orso, Rome to Florence bus times

Buses run hourly between Relais Orso, Rome and Florence. The earliest departure is at 5:42 AM in the morning, and the last departure from Relais Orso, Rome is at 10:04 PM which arrives into Florence at 2:10 AM. All services require a transfer at Zanardelli and take an average of 4h 29m. The schedules shown below are for the next available departures.

Departing Wednesday, April 29, 2026

2:17 PM → 7:05 PM
4h 47m • 1 change
3:32 PM → 7:50 PM
4h 17m • 1 change
4:02 PM → 8:15 PM
4h 12m • 1 change
4:45 PM → 9:15 PM
4h 29m • 1 change
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Departing Thursday, April 30, 2026

5:57 AM → 10:15 AM
4h 17m • 1 change
7:13 AM → 11:10 AM
3h 56m • 1 change
7:53 AM → 12:15 PM
4h 21m • 1 change
8:32 AM → 12:45 PM
4h 12m • 1 change
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Departing Friday, May 1, 2026

5:42 AM → 10:15 AM
4h 32m • 1 change
6:46 AM → 11:10 AM
4h 23m • 1 change
7:20 AM → 11:30 AM
4h 9m • 1 change
8:03 AM → 12:15 PM
4h 11m • 1 change
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Departing Saturday, May 2, 2026

5:43 AM → 10:15 AM
4h 31m • 1 change
6:58 AM → 11:10 AM
4h 11m • 1 change

Frequently asked questions

Want to know about travelling from Relais Orso, Rome to Florence? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.

Map of how to get from Relais Orso, Rome to Florence.

Launch map view

Distance: 285.1 km
Duration: 4h 29m

What companies run services between Relais Orso, Rome, Italy and Florence, Italy?

FlixBus operates a bus from Roma, Autostazione Tiburtina to Florence Villa Constanza Bus Station hourly. Tickets cost €19–35 and the journey takes 3h 15m. Three other operators also service this route.

Operators