The average bus between Rehovot and Safed takes 3h 9m and the fastest bus takes 2h 56m. There is a bus service every few hours from Rehovot to Safed. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run every 2 hours between Rehovot and Safed. The earliest departure is at 6:43 AM in the morning, and the last departure from Rehovot is at 10:47 PM which arrives into Safed at 2:11 AM. All services require a transfer, and take on average 3h 9m. The schedules shown below are for the next available departures.

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2h 58m • 1 changeArrives next day

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3h 16m • 1 changeWant to know about travelling from Rehovot to Safed? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from Rehovot to Safed. However, there are services departing from Herzl/Weizmann station and arriving at מרכז מסחרי/צה''ל station via Aluf Sadeh Terminal station. The journey, including transfers, takes approximately 3h 9m.
Rehovot to Safed bus services, operated by Egged, depart from Herzl/Weizmann station.
Rehovot to Safed bus services, operated by Nateeve Express, arrive at מרכז מסחרי/צה''ל station.
The distance between Rehovot and Safed is 135.2 km. The road distance is 178 km.
You can take a bus from Herzl/Weizmann to מרכז מסחרי/צה''ל via Aluf Sadeh Terminal in around 3h 28m.