The average bus between Prestwick and Carlisle takes 3h 35m and the fastest bus takes 3h 5m. The bus service runs several times per day from Prestwick to Carlisle. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run 3 times a day between Prestwick and Carlisle. The earliest departure is at 7:18 AM in the morning, and the last departure from Prestwick is at 11:50 PM which arrives into Carlisle at 10:45 AM. All services require a transfer, and take on average 3h 35m. The schedules shown below are for the next available departures.

3h 27m • 1 change

3h 15m • 1 change
Arrives next day

3h 5m • 1 change
Arrives next day

10h 55m • 1 change

3h 27m • 1 change

3h 15m • 1 change
Arrives next day

3h 5m • 1 change

3h 20m • 1 change

3h 15m • 1 change
Arrives next day

3h 5m • 1 change
Want to know about travelling from Prestwick to Carlisle? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from Prestwick to Carlisle. However, there are services departing from Prestwick station and arriving at Carlisle station via Buchanan Bus Station station. The journey, including transfers, takes approximately 3h 35m.
Prestwick to Carlisle bus services, operated by Stagecoach West Scotland, depart from Station Road.
Prestwick to Carlisle bus services, operated by Stagecoach West Scotland, arrive at Bus Station.
The distance between Prestwick and Carlisle is 125.6 km. The road distance is 205 km.
You can take a bus from Station Road to Bus Station via Buchanan Bus Station in around 3h 42m.