The average bus between Prague and Wertheim takes 9h 21m and the fastest bus takes 7h 4m. The bus service runs several times per day from Prague to Wertheim. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run 4 times a day between Prague and Wertheim. The earliest departure is at 4:10 AM at night, and the last departure from Prague is at 9:50 PM which arrives into Wertheim at 10:28 AM. All services require a transfer at Nuremberg central bus station and take an average of 9h 21m. The schedules shown below are for the next available departures.


11h 5m • 2 changes


7h 10m • 2 changes


7h 24m • 2 changes
Arrives next day


9h 47m • 2 changes


11h 5m • 2 changes


7h 10m • 2 changes


7h 24m • 2 changes
Arrives next day


10h 57m • 2 changes


11h 5m • 2 changes


7h 10m • 2 changes


7h 24m • 2 changes
Arrives next day


9h 47m • 2 changes


11h 5m • 2 changes


7h 10m • 2 changes


7h 24m • 2 changes
Arrives next day


9h 47m • 2 changes


11h 5m • 2 changes


7h 10m • 2 changes


7h 24m • 2 changes
Arrives next day


7h 4m • 2 changes
Want to know about travelling from Prague to Wertheim? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from Prague to Wertheim. However, there are services departing from Prague station and arriving at Wertheim station via Nuremberg central bus station station. The journey, including transfers, takes approximately 9h 21m.
Prague to Wertheim bus services, operated by FlixBus, depart from Prague station.
Prague to Wertheim bus services, operated by FlixBus, arrive at Wertheim, ZOB station.
The distance between Prague and Wertheim is 353.5 km. The road distance is 441 km.
You can take a bus from Prague to Wertheim, ZOB via Nuremberg central bus station and Würzburg, Hauptbahnhof ZOB in around 7h 48m.