The average bus between Prague and Siena takes 18h 13m and the fastest bus takes 16h 55m. The bus runs, on average, 6 times per week from Prague to Siena. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run 6 times a week between Prague and Siena. The earliest departure is at 5:30 PM in the evening, and the last departure from Prague is at 9:25 PM which arrives into Siena at 2:20 PM. All services require a transfer, and take on average 18h 13m. The schedules shown below are for the next available departures.
Want to know about travelling from Prague to Siena? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from Prague to Siena. However, there are services departing from Prague station and arriving at Siena station via Florence Villa Constanza Bus Station station. The journey, including transfers, takes approximately 18h 13m.
Prague to Siena bus services, operated by FlixBus, depart from Praha, ÚAN Florenc station.
Prague to Siena bus services, operated by FlixBus, arrive at Siena station.
Book your Prague to Siena bus tickets online with FlixBus.
The distance between Prague and Siena is 788.6 km. The road distance is 1,086 km.
You can take a bus from Praha, ÚAN Florenc to Siena via Florence Villa Constanza Bus Station in around 17h.
