The average bus between Prague and Osijek takes 15h 22m and the fastest bus takes 12h 50m. The bus service runs several times per day from Prague to Osijek. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run 4 times a day between Prague and Osijek. The earliest departure is at 2:20 AM at night, and the last departure from Prague is at 11:25 PM which arrives into Osijek at 3:10 PM. All services require a transfer, and take on average 15h 22m. The schedules shown below are for the next available departures.

16h 30m • 1 change
12h 50m • 1 changeArrives next day

17h 55m • 1 changeArrives next day

15h 19m • 1 change
16h 30m • 1 change
12h 50m • 1 changeArrives next day

17h 55m • 1 changeArrives next day

15h 19m • 1 change
16h 30m • 1 change
12h 50m • 1 changeArrives next day

17h 55m • 1 changeArrives next day

15h 19m • 1 changeWant to know about travelling from Prague to Osijek? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from Prague to Osijek. However, there are services departing from Prague station and arriving at Osijek station via Zagreb. The journey, including transfers, takes approximately 15h 22m.
Prague to Osijek bus services, operated by FlixBus, depart from Praha, Hlavní Nádraží station.
Prague to Osijek bus services, operated by FlixBus, arrive at Osijek bus station.
Book your Prague to Osijek bus tickets online with FlixBus.
The distance between Prague and Osijek is 596.7 km. The road distance is 932 km.
You can take a bus from Praha, Hlavní Nádraží to Osijek bus station via Zagreb in around 14h 25m.