The average bus between Prague and Milotice takes 5h 44m and the fastest bus takes 4h 54m. There is a bus service every few hours from Prague to Milotice. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run every 2 hours between Prague and Milotice. The earliest departure is at 3:35 AM at night, and the last departure from Prague is at 11:15 PM which arrives into Milotice at 7:39 AM. All services require a transfer at Brno and take an average of 5h 44m. The schedules shown below are for the next available departures.



5h 4m • 3 changes


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4h 58m • 3 changes


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5h 9m • 3 changes


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5h 3m • 3 changes


5h 9m • 3 changes


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5h 3m • 3 changes


5h 4m • 3 changes


4h 54m • 3 changes


5h 9m • 3 changes


4h 59m • 3 changes


5h 3m • 3 changesWant to know about travelling from Prague to Milotice? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from Prague to Milotice. However, there are services departing from Prague station and arriving at Milotice station via Brno. The journey, including transfers, takes approximately 5h 44m.
Prague to Milotice bus services, operated by FlixBus, depart from Praha, ÚAN Florenc station.
Prague to Milotice bus services, operated by FlixBus, arrive at Kyjov, aut. st. station.
The distance between Prague and Milotice is 233.3 km. The road distance is 285 km.
You can take a bus from Praha, ÚAN Florenc to Milotice, náves via Brno, Hlavní nádraží, Tržní, and Kyjov, aut. st. in around 5h 46m.