The average bus between Portland and South Lake Union takes 4h 58m and the fastest bus takes 4h 13m. The bus service runs several times per day from Portland to South Lake Union. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run 5 times a day between Portland and South Lake Union. The earliest departure is at 7:00 AM in the morning, and the last departure from Portland is at 10:20 PM which arrives into South Lake Union at 6:23 AM. All services require a transfer at Seattle Bus Station and take an average of 4h 58m. The schedules shown below are for the next available departures.

4h 43m • 1 change

4h 37m • 1 change

4h 18m • 1 change
Arrives next day

6h 23m • 1 change

4h 38m • 1 change

4h 43m • 1 change

4h 37m • 1 change

4h 18m • 1 change

4h 38m • 1 change

4h 43m • 1 change

4h 37m • 1 change

4h 18m • 1 change

4h 38m • 1 change

4h 43m • 1 change

4h 37m • 1 change

4h 18m • 1 change

4h 38m • 1 change

4h 43m • 1 change

4h 37m • 1 change

4h 18m • 1 change

4h 21m • 1 change

4h 26m • 1 change

4h 21m • 1 change

4h 13m • 1 change
Want to know about travelling from Portland to South Lake Union? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from Portland to South Lake Union. However, there are services departing from Portland station and arriving at South Lake Union station via Seattle Bus Station station. The journey, including transfers, takes approximately 4h 58m.
Portland to South Lake Union bus services, operated by Flixbus USA, depart from Portland Curbside Bus Stop station.
Portland to South Lake Union bus services, operated by Flixbus USA, arrive at Seattle Bus Station.
The distance between Portland and South Lake Union is 235 km. The road distance is 283 km.
Flixbus USA operates a bus from Portland Curbside Bus Stop to Seattle Bus Station 4 times a day. Tickets cost $22–40 and the journey takes 3h 35m. Greyhound USA also services this route once daily.