The average bus between Portland and Issaquah takes 5h 16m and the fastest bus takes 4h 18m. The bus service runs several times per day from Portland to Issaquah. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run 5 times a day between Portland and Issaquah. The earliest departure is at 7:00 AM in the morning, and the last departure from Portland is at 10:20 PM which arrives into Issaquah at 6:59 AM. All services require a transfer at Seattle Bus Station and take an average of 5h 16m. The schedules shown below are for the next available departures.

4h 39m • 1 change

4h 34m • 1 change

4h 35m • 1 change

4h 18m • 1 change

4h 39m • 1 change

4h 34m • 1 change

4h 35m • 1 change

4h 18m • 1 change

4h 39m • 1 change

4h 34m • 1 change

4h 35m • 1 change

4h 18m • 1 change

4h 39m • 1 change

4h 34m • 1 change

4h 35m • 1 change

4h 18m • 1 change

4h 39m • 1 change

4h 34m • 1 change

4h 35m • 1 change

4h 18m • 1 change

4h 55m • 1 change

4h 33m • 1 change

4h 50m • 1 change
Arrives next day

4h 57m • 1 change
Want to know about travelling from Portland to Issaquah? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from Portland to Issaquah. However, there are services departing from Portland station and arriving at Issaquah station via Seattle Bus Station station. The journey, including transfers, takes approximately 5h 16m.
Portland to Issaquah bus services, operated by Flixbus USA, depart from Portland Curbside Bus Stop station.
Portland to Issaquah bus services, operated by Flixbus USA, arrive at Seattle Bus Station.
The distance between Portland and Issaquah is 228.5 km. The road distance is 306 km.
Flixbus USA operates a bus from Portland Curbside Bus Stop to Seattle Bus Station 4 times a day. Tickets cost $23–40 and the journey takes 3h 35m. Greyhound USA also services this route once daily.