Point Loma to Irvine Buses

Point Loma to Irvine buses

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Trip Overview

The average bus between Point Loma and Irvine takes 3h 42m and the fastest bus takes 3h 11m. There is at least one bus per day from Point Loma to Irvine. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.

3h 42m
Duration: 107 mi
Distance: $27
Average price: Once daily
Frequency

Bus, line 53 bus

best

Take the bus from San Diego to Anaheim Regional Transportation Intermodal Centerbus FlixBus N2003 / ...
Take the bus from Artic - Dock 4 to Main-Harvardbus 53

4h 3m

$18–32

Point Loma to Irvine bus times

Buses run once daily between Point Loma and Irvine. The earliest departure is at 7:47 AM in the morning, and the last departure from Point Loma is at 9:49 PM which arrives into Irvine at 1:00 AM. All services require a transfer at Old Town Transit Center and take an average of 3h 42m. The schedules shown below are for the next available departures.

Departing Friday, November 6, 2026

7:47 AM → 11:44 AM
3h 57m • 2 changes
11:15 AM → 2:41 PM
3h 26m • 2 changes
11:45 AM → 4:11 PM
4h 26m • 2 changes
7:18 PM → 10:32 PM
3h 14m • 2 changes
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Departing Saturday, November 7, 2026

7:49 AM → 11:39 AM
3h 50m • 2 changes
11:15 AM → 2:39 PM
3h 24m • 2 changes
11:45 AM → 4:09 PM
4h 24m • 2 changes
7:18 PM → 10:50 PM
3h 32m • 2 changes

Frequently asked questions

Want to know about travelling from Point Loma to Irvine? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.

What companies run services between Point Loma, CA, USA and Irvine, CA, USA?

You can take a bus from Rosecrans St & Canon St to Main-Harvard via Old Town Transit Center, San Diego, Anaheim Regional Transportation Intermodal Center, and Artic - Dock 4 in around 4h 3m.

Operators