The average bus between Pittsburgh and Missouri takes 21h 42m and the fastest bus takes 20h 10m. The bus service runs several times per day from Pittsburgh to Missouri. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run 3 times a day between Pittsburgh and Missouri. The earliest departure is at 1:25 AM at night, and the last departure from Pittsburgh is at 8:00 PM which arrives into Missouri at 7:10 PM. All services require a transfer, and take on average 21h 42m. The schedules shown below are for the next available departures.

19h 35m • 1 change
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19h 10m • 1 change
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23h 10m • 1 change

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19h 10m • 1 change
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23h 10m • 1 change

19h 35m • 1 change
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19h 10m • 1 change
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23h 10m • 1 change

19h 35m • 1 change
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19h 10m • 1 change
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23h 10m • 1 change
Want to know about travelling from Pittsburgh to Missouri? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from Pittsburgh to Missouri. However, there are services departing from Pittsburgh station and arriving at Missouri station via St Louis Bus Station station. The journey, including transfers, takes approximately 21h 42m.
Pittsburgh to Missouri bus services, operated by Greyhound USA, depart from Pittsburgh Intermodal Station.
Pittsburgh to Missouri bus services, operated by Greyhound USA, arrive at Kansas City Bus Station.
Book your Pittsburgh to Missouri bus tickets online with Greyhound USA.
The distance between Pittsburgh and Missouri is 1,091.7 km. The road distance is 1,370 km.
You can take a bus from Pittsburgh Intermodal Station to Kansas City Bus Station via St Louis Bus Station in around 17h 56m.