Rome2Rio

Pittsburgh to Irvine buses

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Trip Overview

The average bus between Pittsburgh and Irvine takes 2d 13h and the fastest bus takes 2d 10h. The bus runs, on average, 4 times per week from Pittsburgh to Irvine. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.

2d 13h
Duration
2,549 mi
Distance
$548
Average price
4 times a week
Frequency

Pittsburgh to Irvine bus times

Buses run 4 times a week between Pittsburgh and Irvine. The service departs Pittsburgh at 10:40 AM in the morning, which arrives into Irvine at 18:19:00. All services require a transfer at St Louis Bus Station and take an average of 2d 13h. The schedules shown below are for the next available departures.

Departing Tuesday, November 10, 2026

  •  → 

    Arrives +2 days

    Greyhound USAGreyhound USAGreyhound USAOCTA2d 10h • 3 changes

Departing Wednesday, November 11, 2026

  •  → 

    Arrives +2 days

    Greyhound USAGreyhound USAGreyhound USAOCTA2d 10h • 3 changes

Departing Thursday, November 12, 2026

  •  → 

    Arrives +2 days

    Greyhound USAGreyhound USAGreyhound USAOCTA2d 10h • 3 changes

Departing Friday, November 13, 2026

  •  → 

    Arrives +3 days

    Greyhound USAGreyhound USAFlixbus USAOCTA2d 21h • 3 changes

Frequently asked questions

Want to know about travelling from Pittsburgh to Irvine? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.

Map of how to get from Pittsburgh to Irvine.ExpandLaunch map view
  • Distance: 2,549.2 mi
  • Duration: 2d 13h

What companies run services between Pittsburgh, PA, USA and Irvine, CA, USA?

You can take a bus from Pittsburgh Intermodal Station to Main-Harvard via St Louis Bus Station, Los Angeles Union Station, Anaheim Regional Transportation Intermodal Center, and Artic - Dock 4 in around 2d 9h.

Operators