The average bus between Phoenix and Des Moines takes 42h 3m and the fastest bus takes 41h. The bus service runs several times per day from Phoenix to Des Moines. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run twice daily between Phoenix and Des Moines. The earliest departure is at 9:35 AM in the morning, and the last departure from Phoenix is at 10:45 PM which arrives into Des Moines at 5:45 PM. All services require a transfer at Oklahoma City Bus Station and take an average of 42h 3m. The schedules shown below are for the next available departures.
Arrives +2 days


45h 20m • 2 changes
Arrives +2 days


43h • 2 changes
Arrives +2 days


45h 20m • 2 changes
Arrives +2 days


43h • 2 changes
Want to know about travelling from Phoenix to Des Moines? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from Phoenix to Des Moines. However, there are services departing from Phoenix station and arriving at Des Moines station via Oklahoma City Bus Station station. The journey, including transfers, takes approximately 42h 3m.
Phoenix to Des Moines bus services, operated by Greyhound USA, depart from Phoenix Bus Station.
Phoenix to Des Moines bus services, operated by Greyhound USA, arrive at Des Moines station.
The distance between Phoenix and Des Moines is 1,858.1 km. The road distance is 2,538 km.
You can take a bus from Phoenix Bus Station to Des Moines via Oklahoma City Bus Station and Kansas City in around 32h 25m.