The average bus between Philadelphia and Natick takes 9h 51m and the fastest bus takes 7h 46m. The bus service runs several times per day from Philadelphia to Natick. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run twice daily between Philadelphia and Natick. The earliest departure is at 2:20 AM at night, and the last departure from Philadelphia is at 8:15 PM which arrives into Natick at 5:47 AM. All services require a transfer at New York Midtown and take an average of 9h 51m. The schedules shown below are for the next available departures.
Arrives next day


7h 46m • 2 changes
Arrives next day


9h 32m • 2 changes


9h 22m • 2 changes


9h 27m • 2 changes


8h 54m • 2 changes


12h 16m • 2 changes


9h 22m • 2 changes


9h 27m • 2 changes


8h 54m • 2 changes


12h 16m • 2 changes
Want to know about travelling from Philadelphia to Natick? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from Philadelphia to Natick. However, there are services departing from Philadelphia station and arriving at Natick station via New York Midtown. The journey, including transfers, takes approximately 9h 51m.
Philadelphia to Natick bus services, operated by Flixbus USA, depart from Philadelphia Bus Station.
Philadelphia to Natick bus services, operated by Flixbus USA, arrive at Boston station.
The distance between Philadelphia and Natick is 411.3 km. The road distance is 600 km.
You can take a bus from Philadelphia Bus Station to Natick Center - South Ave opp Adams St via New York Midtown, Boston, and South Station - Bus Terminal Gate B1/B2 in around 8h 55m.