The average bus between Philadelphia, PA and Buffalo takes 11h 49m and the fastest bus takes 10h 30m. The bus service runs several times per day from Philadelphia, PA to Buffalo. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run 3 times a day between Philadelphia, PA and Buffalo. The earliest departure is at 5:20 AM in the morning, and the last departure from Philadelphia, PA is at 5:00 PM which arrives into Buffalo at 5:00 AM. All services require a transfer at Philadelphia Bus Station and take an average of 11h 49m. The schedules shown below are for the next available departures.

11h 40m • 1 change

10h 30m • 1 change
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12h • 1 change

11h 40m • 1 change

10h 30m • 1 change
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12h • 1 change

11h 40m • 1 change

10h 30m • 1 change
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12h • 1 change

11h 40m • 1 change

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18h 30m • 1 change
Want to know about travelling from Philadelphia, PA to Buffalo? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from Philadelphia, PA to Buffalo. However, there are services departing from Philadelphia, PA station and arriving at Buffalo station via Newark Penn Station station. The journey, including transfers, takes approximately 11h 49m.
Philadelphia, PA to Buffalo bus services, operated by Flixbus USA, depart from Philadelphia Bus Station.
Philadelphia, PA to Buffalo bus services, operated by Flixbus USA, arrive at Buffalo station.
The distance between Philadelphia, PA and Buffalo is 449.8 km. The road distance is 776 km.
You can take a vehicle from Philadelphia, PA to Buffalo via Philadelphia Bus Station and Newark Penn Station in around 10h 37m.