The average bus between Perugia and Messina takes 13h 42m and the fastest bus takes 12h 15m. The bus service runs several times per day from Perugia to Messina. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run 3 times a day between Perugia and Messina. The earliest departure is at 6:15 AM in the morning, and the last departure from Perugia is at 8:45 PM which arrives into Messina at 11:10 AM. All services require a transfer, and take on average 13h 42m. The schedules shown below are for the next available departures.
Arrives next day

14h 30m • 1 change
Arrives next day

14h 25m • 1 change

13h 35m • 1 change
Arrives next day

16h • 1 change
Arrives next day

14h 25m • 1 change

13h 35m • 1 change
Arrives next day

12h 15m • 1 change
Arrives next day

14h 25m • 1 change

13h 35m • 1 change
Arrives next day

12h 15m • 1 change
Arrives next day

14h 25m • 1 change

13h 35m • 1 change
Arrives next day

12h 15m • 1 change
Arrives next day

14h 25m • 1 change
Want to know about travelling from Perugia to Messina? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from Perugia to Messina. However, there are services departing from Perugia station and arriving at Messina station via Roma, Autostazione Tiburtina. The journey, including transfers, takes approximately 13h 42m.
Perugia to Messina bus services, operated by FlixBus, depart from Perugia station.
Perugia to Messina bus services, operated by FlixBus, arrive at Messina station.
Book your Perugia to Messina bus tickets online with FlixBus and Sulga Autolinee.
The distance between Perugia and Messina is 608.4 km. The road distance is 879 km.
You can take a bus from Perugia to Messina via Roma, Autostazione Tiburtina in around 12h 50m.