The average bus between Perugia and Lyon takes 14h 2m and the fastest bus takes 12h 50m. The bus service runs several times per day from Perugia to Lyon. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run 3 times a day between Perugia and Lyon. The earliest departure is at 7:00 AM in the morning, and the last departure from Perugia is at 5:15 PM which arrives into Lyon at 8:45 AM. All services require a transfer, and take on average 14h 2m. The schedules shown below are for the next available departures.

12h 50m • 1 change
Arrives next day

13h 55m • 1 change
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13h 30m • 1 change
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15h 30m • 1 change

12h 50m • 1 change
Arrives next day

13h 55m • 1 change
Arrives next day

13h 30m • 1 change
Arrives next day

15h 30m • 1 change

12h 50m • 1 change
Arrives next day

13h 55m • 1 change
Arrives next day

13h 30m • 1 change
Arrives next day

15h 30m • 1 change
Want to know about travelling from Perugia to Lyon? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from Perugia to Lyon. However, there are services departing from Perugia station and arriving at Lyon station via Florence Villa Constanza Bus Station station. The journey, including transfers, takes approximately 14h 2m.
Perugia to Lyon bus services, operated by FlixBus, depart from Perugia station.
Perugia to Lyon bus services, operated by FlixBus, arrive at Lyon station.
Book your Perugia to Lyon bus tickets online with FlixBus and BlaBlaCar Bus.
The distance between Perugia and Lyon is 666.4 km. The road distance is 907 km.
You can take a bus from Perugia to Lyon via Florence Villa Constanza Bus Station in around 14h 10m.