The average bus between Pantheon and Siena takes 3h 30m and the fastest bus takes 3h 10m. The bus service runs several times per day from Pantheon to Siena. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run every 3 hours between Pantheon and Siena. The earliest departure is at 5:53 AM in the morning, and the last departure from Pantheon is at 9:10 PM which arrives into Siena at 12:40 AM. All services require a transfer at Corso/Minghetti and take an average of 3h 30m. The schedules shown below are for the next available departures.

3h 10m • 1 change

3h 27m • 1 change

3h 31m • 1 change

3h 40m • 1 change

3h 16m • 1 change

3h 26m • 1 change

3h 25m • 1 change

3h 47m • 1 change

3h 21m • 1 change

3h 21m • 1 change

3h 30m • 1 change

3h 37m • 1 change

3h 10m • 1 change

3h 27m • 1 change

3h 31m • 1 change

3h 40m • 1 change

3h 21m • 1 change

3h 23m • 1 change

3h 29m • 1 change

3h 21m • 1 change

3h 38m • 1 change

3h 29m • 1 change

3h 25m • 1 change

3h 35m • 1 change
Want to know about travelling from Pantheon to Siena? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from Pantheon to Siena. However, there are services departing from Pantheon station and arriving at Siena station via Siena. The journey, including transfers, takes approximately 3h 30m.
Pantheon to Siena bus services, operated by ATAC S.p.A. Azienda per la mobilità, depart from Roma, Autostazione Tiburtina station.
Pantheon to Siena bus services, operated by ATAC S.p.A. Azienda per la mobilità, arrive at Siena station.
Book your Pantheon to Siena bus tickets online with ATAC S.p.A. Azienda per la mobilità and FlixBus.
The distance between Pantheon and Siena is 183.6 km. The road distance is 239 km.
FlixBus operates a bus from Roma, Autostazione Tiburtina to Siena every 3 hours. Tickets cost €16–27 and the journey takes 2h 39m. AutoLinee Moretti also services this route 3 times a week.