The average bus between Palermo and Prato takes 22h 17m and the fastest bus takes 21h 15m. The bus service runs several times per day from Palermo to Prato. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run twice daily between Palermo and Prato. The earliest departure is at 3:25 PM in the afternoon, and the last departure from Palermo is at 9:10 PM which arrives into Prato at 6:25 PM. All services require a transfer, and take on average 22h 17m. The schedules shown below are for the next available departures.
Arrives next day

23h 10m • 1 change
Arrives next day

21h 15m • 1 change
Arrives next day

23h 10m • 1 change
Arrives next day

21h 15m • 1 change
Arrives next day

23h 10m • 1 change
Arrives next day

21h 15m • 1 change
Want to know about travelling from Palermo to Prato? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from Palermo to Prato. However, there are services departing from Palermo station and arriving at Prato station via Florence Villa Constanza Bus Station station. The journey, including transfers, takes approximately 22h 17m.
Palermo to Prato bus services, operated by FlixBus, depart from Palermo station.
Palermo to Prato bus services, operated by FlixBus, arrive at Florence Villa Constanza Bus Station.
Book your Palermo to Prato bus tickets online with FlixBus.
The distance between Palermo and Prato is 666.2 km. The road distance is 1,290 km.
FlixBus operates a bus from Palermo to Florence Villa Constanza Bus Station twice daily. Tickets cost €90–150 and the journey takes 17h 20m. Autoservizi Salemi Srl also services this route once a week.