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The bus between Palermo and Isernia takes 17h 44m. There is at least one bus per day from Palermo to Isernia. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run once daily between Palermo and Isernia. The service departs Palermo at 6:00 PM in the evening, which arrives into Isernia at 11:44:00. All services require a transfer at Caserta pzza Garibaldi and take an average of 17h 44m. The schedules shown below are for the next available departures.
Want to know about travelling from Palermo to Isernia? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from Palermo to Isernia. However, there are services departing from Palermo Terminal Bus station and arriving at Isernia station via Caserta pzza Garibaldi station. The journey, including transfers, takes approximately 17h 44m.
Palermo to Isernia bus services, operated by Autoservizi Salemi Srl, depart from Palermo Terminal Bus station.
Palermo to Isernia bus services, operated by FlixBus, arrive at Isernia station.
Book your Palermo to Isernia bus tickets online with Omio.
The distance between Palermo and Isernia is 392.7 km.
You can take a bus from Palermo Terminal Bus to Isernia via Caserta pzza Garibaldi and Caserta Terminal Bus in around 12h 4m.
