The average bus between Palermo and Genoa takes 22h 7m and the fastest bus takes 21h 15m. The bus service runs several times per day from Palermo to Genoa. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run twice daily between Palermo and Genoa. The earliest departure is at 3:25 PM in the afternoon, and the last departure from Palermo is at 9:10 PM which arrives into Genoa at 6:25 PM. All services require a transfer, and take on average 22h 7m. The schedules shown below are for the next available departures.
Arrives next day

23h • 1 change
Arrives next day

21h 15m • 1 change
Arrives next day

23h • 1 change
Arrives next day

21h 15m • 1 change
Want to know about travelling from Palermo to Genoa? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from Palermo to Genoa. However, there are services departing from Palermo station and arriving at Genoa station via Florence Villa Constanza Bus Station station. The journey, including transfers, takes approximately 22h 7m.
Palermo to Genoa bus services, operated by FlixBus, depart from Palermo station.
Palermo to Genoa bus services, operated by FlixBus, arrive at Genoa station.
Book your Palermo to Genoa bus tickets online with FlixBus.
The distance between Palermo and Genoa is 787.9 km. The road distance is 1,502 km.
You can take a bus from Palermo to Genoa via Florence Villa Constanza Bus Station in around 21h.