The average bus between Oxford and Manchester takes 5h 47m and the fastest bus takes 4h 50m. The bus service runs several times per day from Oxford to Manchester. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run every 4 hours between Oxford and Manchester. The earliest departure is at 12:50 AM at night, and the last departure from Oxford is at 6:50 PM which arrives into Manchester at 12:25 AM. All services require a transfer, and take on average 5h 47m. The schedules shown below are for the next available departures.

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4h 50m • 1 changeWant to know about travelling from Oxford to Manchester? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from Oxford to Manchester. However, there are services departing from Gloucester Green Bus Station and arriving at Manchester Central Coach Station via Milton Keynes Coachway station. The journey, including transfers, takes approximately 5h 47m.
Oxford to Manchester bus services, operated by National Express, depart from Gloucester Green Bus Station.
Oxford to Manchester bus services, operated by National Express, arrive at Manchester Central Coach Station.
Book your Oxford to Manchester bus tickets online with Omio.
The distance between Oxford and Manchester is 203.3 km. The road distance is 244 km.
You can take a bus from Gloucester Green Bus Station to Manchester Central Coach Station via Milton Keynes Coachway in around 5h 38m.