Rome2Rio

Orlando to Missouri buses

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Trip Overview

The average bus between Orlando and Missouri takes 29h 34m and the fastest bus takes 27h 50m. The bus service runs several times per day from Orlando to Missouri. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.

29h 34m
Duration
1,246 mi
Distance
$261
Average price
Twice daily
Frequency

Orlando to Missouri bus times

Buses run twice daily between Orlando and Missouri. The earliest departure is at 12:55 AM at night, and the last departure from Orlando is at 2:40 PM which arrives into Missouri at 7:45 PM. All services require a transfer at Atlanta Bus Station and take an average of 29h 34m. The schedules shown below are for the next available departures.

Departing Sunday, November 15, 2026

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    Arrives next day

    Flixbus USAFlixbus USAGreyhound USA30h 5m • 2 changes

Departing Monday, November 16, 2026

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    Arrives next day

    Flixbus USAGreyhound USAGreyhound USA27h 50m • 2 changes

Departing Tuesday, November 17, 2026

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    Arrives next day

    Flixbus USAGreyhound USAGreyhound USA27h 50m • 2 changes

Departing Wednesday, November 18, 2026

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    Arrives next day

    Flixbus USAGreyhound USAGreyhound USA27h 50m • 2 changes
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    Arrives next day

    Flixbus USAFlixbus USAGreyhound USA30h 5m • 2 changes

Departing Thursday, November 19, 2026

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    Arrives next day

    Flixbus USAGreyhound USAGreyhound USA27h 50m • 2 changes
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    Arrives next day

    Flixbus USAFlixbus USAGreyhound USA32h 15m • 2 changes

Departing Friday, November 20, 2026

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    Arrives next day

    Flixbus USAGreyhound USAGreyhound USA27h 50m • 2 changes
  •  → 

    Arrives next day

    Flixbus USAFlixbus USAGreyhound USA30h 5m • 2 changes

Frequently asked questions

Want to know about travelling from Orlando to Missouri? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.

Map of how to get from Orlando to Missouri.ExpandLaunch map view
  • Distance: 1,245.6 mi
  • Duration: 29h 34m

What companies run services between Orlando, FL, USA and Missouri, USA?

You can take a bus from Orlando Bus Station to Kansas City Bus Station via Atlanta Bus Station and St Louis Bus Station in around 24h 55m.

Operators