The average bus between Orlando and Key West takes 11h 44m and the fastest bus takes 10h 22m. The bus service runs several times per day from Orlando to Key West. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run twice daily between Orlando and Key West. The earliest departure is at 12:45 AM at night, and the last departure from Orlando is at 11:05 PM which arrives into Key West at 1:02 PM. All services require a transfer at Miami Airport Station and take an average of 11h 44m. The schedules shown below are for the next available departures.
Want to know about travelling from Orlando to Key West? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from Orlando to Key West. However, there are services departing from Orlando station and arriving at Key West station via Miami Airport Station station. The journey, including transfers, takes approximately 11h 44m.
Orlando to Key West bus services, operated by Greyhound USA, depart from Orlando Bus Station.
Orlando to Key West bus services, operated by Greyhound USA, arrive at N Roosevelt & 3rd Street station.
Book your Orlando to Key West bus tickets online with Greyhound USA, Key West Transit and Flixbus USA.
The distance between Orlando and Key West is 444.7 km. The road distance is 633 km.
You can take a bus from Orlando Bus Station to N Roosevelt & 3rd Street via Miami Airport Station, Big Pine Key, and Big Pine Key - CVS / MM30 in around 11h 46m.