The average bus between Opio and Lyon takes 8h 30m and the fastest bus takes 7h 21m. The bus service runs several times per day from Opio to Lyon. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run every 3 hours between Opio and Lyon. The earliest departure is at 6:03 AM in the morning, and the last departure from Opio is at 8:13 PM which arrives into Lyon at 3:55 AM. All services require a transfer at Gare SNCF and take an average of 8h 30m. The schedules shown below are for the next available departures.

8h 16m • 1 change

7h 47m • 1 change

8h 53m • 1 change

9h 11m • 1 change

7h 25m • 1 change

10h 11m • 1 change

10h 41m • 1 change

8h 11m • 1 change

7h 21m • 1 change

9h 31m • 1 change

10h 31m • 1 change

8h 41m • 1 change

8h 16m • 1 change

7h 47m • 1 change

8h 53m • 1 change

9h 11m • 1 change

8h 16m • 1 change

7h 47m • 1 change

8h 53m • 1 change

9h 11m • 1 change
Want to know about travelling from Opio to Lyon? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from Opio to Lyon. However, there are services departing from Opio station and arriving at Lyon station via Lyon. The journey, including transfers, takes approximately 8h 30m.
Opio to Lyon bus services, operated by ZOU! Proximité, depart from Antibes station.
Opio to Lyon bus services, operated by ZOU! Proximité, arrive at Lyon station.
The distance between Opio and Lyon is 286.3 km. The road distance is 487 km.
FlixBus operates a bus from Antibes to Lyon twice daily. Tickets cost €35–65 and the journey takes 6h 10m.