The average bus between Nuremberg and Mainz takes 4h 57m and the fastest bus takes 4h 20m. The bus service runs several times per day from Nuremberg to Mainz. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run 5 times a day between Nuremberg and Mainz. The earliest departure is at 2:55 AM at night, and the last departure from Nuremberg is at 5:15 PM which arrives into Mainz at 10:35 PM. All services require a transfer, and take on average 4h 57m. The schedules shown below are for the next available departures.

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Want to know about travelling from Nuremberg to Mainz? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from Nuremberg to Mainz. However, there are services departing from Nuremberg station and arriving at Mainz station via Frankfurt central train station station. The journey, including transfers, takes approximately 4h 57m.
Nuremberg to Mainz bus services, operated by FlixBus, depart from Nuremberg central bus station.
Nuremberg to Mainz bus services, operated by FlixBus, arrive at Frankfurt central train station.
Book your Nuremberg to Mainz bus tickets online with FlixBus.
The distance between Nuremberg and Mainz is 209.6 km. The road distance is 262 km.
FlixBus operates a bus from Nuremberg central bus station to Frankfurt central train station hourly. Tickets cost €15–27 and the journey takes 2h 45m.