The average bus between Novi Ligure and Messina takes 24h 3m and the fastest bus takes 21h 10m. The bus service runs several times per day from Novi Ligure to Messina. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run twice daily between Novi Ligure and Messina. The earliest departure is at 9:10 AM in the morning, and the last departure from Novi Ligure is at 6:30 PM which arrives into Messina at 7:50 PM. All services require a transfer at Serravalle Scrivia and take an average of 24h 3m. The schedules shown below are for the next available departures.
Arrives next day


21h 10m • 2 changes
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25h 20m • 2 changes
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21h 10m • 2 changes
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29h 30m • 2 changes
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21h 10m • 2 changes
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29h 30m • 2 changes
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21h 10m • 2 changes
Arrives next day


25h 20m • 2 changes
Want to know about travelling from Novi Ligure to Messina? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from Novi Ligure to Messina. However, there are services departing from Novi Ligure station and arriving at Messina station via Milano, Autostazione Lampugnano. The journey, including transfers, takes approximately 24h 3m.
Novi Ligure to Messina bus services, operated by AUTOLINEE VAL BORBERA S.r.l., depart from Serravalle Scrivia station.
Novi Ligure to Messina bus services, operated by AUTOLINEE VAL BORBERA S.r.l., arrive at Messina station.
The distance between Novi Ligure and Messina is 921.9 km. The road distance is 1,392 km.
You can take a bus from Novi Ligure to Messina via Serravalle Scrivia and Milano, Autostazione Lampugnano in around 20h 53m.