The average bus between Niscemi and Messina takes 4h 24m and the fastest bus takes 3h 48m. The bus service runs several times per day from Niscemi to Messina. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run 3 times a day between Niscemi and Messina. The earliest departure is at 5:42 AM in the morning, and the last departure from Niscemi is at 5:02 PM which arrives into Messina at 9:25 PM. All services require a transfer, and take on average 4h 24m. The schedules shown below are for the next available departures.

4h 18m • 1 change

3h 48m • 1 change

5h 3m • 1 change

4h 23m • 1 change

4h 18m • 1 change

3h 48m • 1 change

5h 3m • 1 change

4h 23m • 1 change

4h 18m • 1 change

3h 48m • 1 change

5h 3m • 1 change

4h 23m • 1 change
Want to know about travelling from Niscemi to Messina? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from Niscemi to Messina. However, there are services departing from Niscemi station and arriving at Messina station via Catania Central Bus Station station. The journey, including transfers, takes approximately 4h 24m.
Niscemi to Messina bus services, operated by Etna Trasporti, depart from Viale Mario Gori, Niscemi station.
Niscemi to Messina bus services, operated by Etna Trasporti, arrive at Messina Piazza della Repubblica station.
The distance between Niscemi and Messina is 154.8 km. The road distance is 186 km.
You can take a bus from Viale Mario Gori, Niscemi to Messina Piazza della Repubblica via Catania Central Bus Station in around 4h 18m.