The average bus between Niagara Falls and Harlem takes 10h 18m and the fastest bus takes 9h 46m. The bus service runs several times per day from Niagara Falls to Harlem. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run every 4 hours between Niagara Falls and Harlem. The earliest departure is at 2:50 AM at night, and the last departure from Niagara Falls is at 11:20 PM which arrives into Harlem at 9:34 AM. All services require a transfer at New York Midtown and take an average of 10h 18m. The schedules shown below are for the next available departures.

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10h 7m • 1 change

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10h 23m • 1 change
Want to know about travelling from Niagara Falls to Harlem? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from Niagara Falls to Harlem. However, there are services departing from Niagara Falls station and arriving at Harlem station via New York Midtown. The journey, including transfers, takes approximately 10h 18m.
Niagara Falls to Harlem bus services, operated by Flixbus USA, depart from Niagara Falls USA station.
Niagara Falls to Harlem bus services, operated by Flixbus USA, arrive at New York Midtown station.
The distance between Niagara Falls and Harlem is 493.1 km. The road distance is 788 km.
Flixbus USA operates a bus from Niagara Falls USA to New York Midtown every 4 hours. Tickets cost $65–120 and the journey takes 9h 15m.