The average bus between Neu-Isenburg and Essen takes 5h 8m and the fastest bus takes 4h 49m. The bus service runs several times per day from Neu-Isenburg to Essen. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run 3 times a day between Neu-Isenburg and Essen. The earliest departure is at 2:21 PM in the afternoon, and the last departure from Neu-Isenburg is at 9:47 PM which arrives into Essen at 2:55 AM. All services require a transfer at Frankfurt and take an average of 5h 8m. The schedules shown below are for the next available departures.

5h 29m • 1 change

4h 49m • 1 change
Arrives next day

5h 8m • 1 change

5h 29m • 1 change

4h 49m • 1 change
Arrives next day

5h 8m • 1 change

5h 29m • 1 change

4h 49m • 1 change
Arrives next day

5h 8m • 1 change

5h 29m • 1 change

4h 49m • 1 change
Arrives next day

5h 8m • 1 change
Want to know about travelling from Neu-Isenburg to Essen? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from Neu-Isenburg to Essen. However, there are services departing from Neu-Isenburg station and arriving at Essen station via Essen central train station station. The journey, including transfers, takes approximately 5h 8m.
Neu-Isenburg to Essen bus services, operated by Kreativ Tours GmbH, depart from Frankfurt Airport station.
Neu-Isenburg to Essen bus services, operated by Kreativ Tours GmbH, arrive at Essen central train station.
The distance between Neu-Isenburg and Essen is 196.2 km. The road distance is 279 km.
FlixBus operates a bus from Frankfurt Airport to Essen central train station 4 times a day. Tickets cost €18–35 and the journey takes 4h 10m.