The average bus between Nashua and Natick takes 2h 59m and the fastest bus takes 2h 15m. The bus service runs several times per day from Nashua to Natick. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run twice daily between Nashua and Natick. The earliest departure is at 7:30 AM in the morning, and the last departure from Nashua is at 7:00 PM which arrives into Natick at 12:16 AM. All services require a transfer, and take on average 2h 59m. The schedules shown below are for the next available departures.

2h 15m • 1 change

2h 42m • 1 change

3h 12m • 1 change

3h 41m • 1 change
Want to know about travelling from Nashua to Natick? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from Nashua to Natick. However, there are services departing from Nashua station and arriving at Natick station via Boston South Buses. The journey, including transfers, takes approximately 2h 59m.
Nashua to Natick bus services, operated by Boston Express, depart from Nashua, NH station.
Nashua to Natick bus services, operated by Boston Express, arrive at Natick Center - South Ave opp Adams St station.
The distance between Nashua and Natick is 54.5 km. The road distance is 101 km.
You can take a bus from Nashua, NH to Natick Center - South Ave opp Adams St via South Station - Bus Terminal Gate B1/B2 in around 3h 10m.