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Mississippi to Durham buses

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Trip Overview

The average bus between Mississippi and Durham takes 22h 11m and the fastest bus takes 17h 50m. The bus service runs several times per day from Mississippi to Durham. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.

22h 11m
Duration
776 mi
Distance
$161
Average price
Twice daily
Frequency

Mississippi to Durham bus times

Buses run twice daily between Mississippi and Durham. The earliest departure is at 2:00 PM in the afternoon, and the last departure from Mississippi is at 5:30 PM which arrives into Durham at 9:10 PM. All services require a transfer, and take on average 22h 11m. The schedules shown below are for the next available departures.

Departing Sunday, November 15, 2026

  •  → 

    Arrives next day

    Greyhound USAGreyhound USA17h 50m • 1 change
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    Arrives next day

    Greyhound USAFlixbus USA26h 40m • 1 change

Departing Monday, November 16, 2026

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    Arrives next day

    Greyhound USAGreyhound USA17h 50m • 1 change
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    Arrives +2 days

    Greyhound USAFlixbus USA31h 40m • 1 change

Departing Tuesday, November 17, 2026

  •  → 

    Arrives next day

    Greyhound USAGreyhound USA17h 50m • 1 change
  •  → 

    Arrives +2 days

    Greyhound USAFlixbus USA31h 40m • 1 change

Departing Wednesday, November 18, 2026

  •  → 

    Arrives next day

    Greyhound USAGreyhound USA17h 50m • 1 change
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    Arrives next day

    Greyhound USAFlixbus USA23h 5m • 1 change

Departing Thursday, November 19, 2026

  •  → 

    Arrives next day

    Greyhound USAGreyhound USA17h 50m • 1 change
  •  → 

    Arrives next day

    Greyhound USAFlixbus USA23h 5m • 1 change

Departing Friday, November 20, 2026

  •  → 

    Arrives next day

    Greyhound USAGreyhound USA17h 50m • 1 change
  •  → 

    Arrives next day

    Greyhound USAFlixbus USA23h 5m • 1 change

Frequently asked questions

Want to know about travelling from Mississippi to Durham? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.

Map of how to get from Mississippi to Durham.ExpandLaunch map view
  • Distance: 775.6 mi
  • Duration: 22h 11m

What companies run services between Mississippi, USA and Durham, NC, USA?

You can take a bus from Jackson to Durham via Atlanta Bus Station in around 16h 20m.

Operators