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Mississauga to Durham buses

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Trip Overview

The average bus between Mississauga and Durham takes 33h 1m and the fastest bus takes 28h 20m. The bus runs, on average, 4 times per week from Mississauga to Durham. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.

33h 1m
Duration
1,055 mi
Distance
$386
Average price
4 times a week
Frequency

Mississauga to Durham bus times

Buses run 4 times a week between Mississauga and Durham. The earliest departure is at 5:46 AM in the morning, and the last departure from Mississauga is at 10:20 PM which arrives into Durham at 4:50 AM. All services require a transfer at New York and take an average of 33h 1m. The schedules shown below are for the next available departures.

Departing Sunday, November 1, 2026

  •  → 

    Arrives +2 days

    GO TransitFlixbus USAFlixbus USAFlixbus USA28h 22m • 3 changes

Departing Monday, November 2, 2026

  •  → 

    Arrives +2 days

    GO TransitFlixbus USAFlixbus USAGreyhound USA30h 30m • 3 changes

Departing Thursday, November 5, 2026

  •  → 

    Arrives +2 days

    GO TransitFlixbus USAFlixbus USAFlixbus USA44h 54m • 3 changes

Departing Friday, November 6, 2026

  •  → 

    Arrives +2 days

    GO TransitFlixbus USAFlixbus USAFlixbus USA28h 20m • 3 changes

Frequently asked questions

Want to know about travelling from Mississauga to Durham? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.

Map of how to get from Mississauga to Durham.ExpandLaunch map view
  • Distance: 1,054.5 mi
  • Duration: 33h 1m

What companies run services between Mississauga, ON, Canada and Durham, NC, USA?

You can take a bus from City Centre Transit Terminal Platform O to Durham via Mississauga, New York, 42 St-Times Square, Canal St, and New York, NY in around 20h 25m.

Operators