The average bus between Milan and Portopiccolo takes 8h 41m and the fastest bus takes 7h 13m. The bus service runs several times per day from Milan to Portopiccolo. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run twice daily between Milan and Portopiccolo. The earliest departure is at 12:10 AM at night, and the last departure from Milan is at 8:15 PM which arrives into Portopiccolo at 6:58 AM. All services require a transfer, and take on average 8h 41m. The schedules shown below are for the next available departures.

8h 3m • 1 change

7h 13m • 1 change
Arrives next day

10h 43m • 1 change

8h 3m • 1 change

7h 13m • 1 change
Arrives next day

10h 43m • 1 change

8h 3m • 1 change

7h 13m • 1 change
Arrives next day

10h 43m • 1 change
Want to know about travelling from Milan to Portopiccolo? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from Milan to Portopiccolo. However, there are services departing from Milan station and arriving at Portopiccolo station via Trieste. The journey, including transfers, takes approximately 8h 41m.
Milan to Portopiccolo bus services, operated by FlixBus, depart from Milano, Autostazione Lampugnano station.
Milan to Portopiccolo bus services, operated by FlixBus, arrive at Trieste station.
Book your Milan to Portopiccolo bus tickets online with FlixBus, APT Gorizia and Arriva Udine.
The distance between Milan and Portopiccolo is 347.5 km. The road distance is 446 km.
BlaBlaCar Bus operates a bus from Milano, Autostazione Lampugnano to Trieste 5 times a day. Tickets cost €35–65 and the journey takes 5h 25m. FlixBus also services this route 5 times a day.