Rome2Rio

Milan to Lyon Perrache buses

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Trip Overview

The average bus between Milan and Lyon Perrache takes 6h 45m and the fastest bus takes 6h 10m. There is a bus service every few hours from Milan to Lyon Perrache. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.

6h 45m
Duration
443 km
Distance
€40
Average price
Hourly
Frequency

Milan to Lyon Perrache bus times

Buses run hourly between Milan and Lyon Perrache. The earliest departure is at 5:45 AM in the morning, and the last departure from Milan is at 11:45 PM which arrives into Lyon Perrache at 6:30 AM. All services run direct with no transfers required, and take on average 6h 45m. The schedules shown below are for the next available departures.

Departing Tuesday, November 10, 2026

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    Arrives next day

    bus bus 6h 35m • Direct
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    Arrives next day

    bus bus 6h 35m • Direct
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    Arrives next day

    bus bus 6h 30m • Direct
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    Arrives next day

    bus bus 6h 20m • Direct
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Departing Wednesday, November 11, 2026

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    bus bus 6h 15m • Direct
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    bus bus 6h 50m • Direct
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    bus bus 6h 40m • Direct
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    bus bus 6h 40m • Direct
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Departing Thursday, November 12, 2026

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    bus bus 6h 15m • Direct
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    bus bus 6h 50m • Direct
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    bus bus 6h 40m • Direct
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    bus bus 6h 40m • Direct
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Departing Friday, November 13, 2026

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    bus bus 6h 15m • Direct
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    bus bus 6h 50m • Direct
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    bus bus 6h 40m • Direct
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    bus bus 6h 40m • Direct
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Departing Saturday, November 14, 2026

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    bus bus 6h 15m • Direct
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    bus bus 6h 50m • Direct
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    bus bus 6h 40m • Direct
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    bus bus 6h 40m • Direct
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Departing Sunday, November 15, 2026

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    bus bus 6h 15m • Direct
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    bus bus 6h 50m • Direct
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    bus bus 6h 40m • Direct
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    bus bus 6h 40m • Direct
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Departing Monday, November 16, 2026

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    bus bus 6h 15m • Direct
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    bus bus 6h 50m • Direct
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    bus bus 6h 40m • Direct
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    bus bus 6h 40m • Direct
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Departing Tuesday, November 17, 2026

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    bus bus 6h 50m • Direct
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    bus bus 6h 40m • Direct

Frequently asked questions

Want to know about travelling from Milan to Lyon Perrache? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.

Map of how to get from Milan to Lyon Perrache.ExpandLaunch map view
  • Distance: 442.9 km
  • Duration: 6h 45m

What companies run services between Milan, Italy and Lyon Perrache, France?

BlaBlaCar Bus operates a bus from Milano, Autostazione Lampugnano to Lyon - Gerland Bus Station hourly. Tickets cost €35–60 and the journey takes 6h 30m. Two other operators also service this route.

Operators